This simulator demonstrates how insulin-driven cellular uptake and aldosterone-regulated renal excretion work together on different timescales to keep serum potassium within its narrow normal range.
Adjust potassium intake, insulin levels, and aldosterone activity to see how serum potassium responds, and watch how the resting membrane potential and simulated ECG change as levels move toward hypokalemia or hyperkalemia.
Sliders let you control dietary potassium load, insulin activity, and aldosterone-driven renal secretion to observe their combined effect on serum potassium and cardiac membrane potential.
About 98 percent of the body's potassium is stored inside cells, so the small amount circulating in blood, which is what a lab test actually measures, is only a thin and tightly guarded slice of the total supply.
This simulator demonstrates how insulin-driven cellular uptake and aldosterone-regulated renal excretion work together on different timescales to keep serum potassium within its narrow normal range.
This simulator demonstrates how insulin-driven cellular uptake and aldosterone-regulated renal excretion work together on different timescales to keep serum potassium within its narrow normal range.
Adjust potassium intake, insulin levels, and aldosterone activity to see how serum potassium responds, and watch how the resting membrane potential and simulated ECG change as levels move toward hypokalemia or hyperkalemia.
About 98 percent of the body's potassium is stored inside cells, so the small amount circulating in blood, which is what a lab test actually measures, is only a thin and tightly guarded slice of the total supply.