The simulation shows arterial pressure perturbing baroreceptor firing rate in real time, tracing how the brainstem's error signal splits into vagal and sympathetic commands that pull heart rate and vessel tone back toward a defended set point within one to two heartbeats.
Trigger a pressure disturbance such as standing up or a hemorrhage event, adjust the baroreflex gain (sensitivity) slider to see stronger or weaker correction, and watch the firing-rate, heart-rate, and blood-pressure traces settle back toward the 120/80 mmHg target.
Perturbation trigger select, baroreflex gain (sensitivity) slider, play/pause, reset trace
Carotid sinus baroreceptor signals were first shown to control blood pressure in the 1920s by Heinrich Ewald Hering and Corneille Heymans, work that earned Heymans the 1938 Nobel Prize in Physiology or Medicine, decades before the reflex arc's millisecond-scale timing could be directly measured.
The simulation shows arterial pressure perturbing baroreceptor firing rate in real time, tracing how the brainstem's error signal splits into vagal and sympathetic commands that pull heart rate and vessel tone back toward a defended set point within one to two heartbeats.
The simulation shows arterial pressure perturbing baroreceptor firing rate in real time, tracing how the brainstem's error signal splits into vagal and sympathetic commands that pull heart rate and vessel tone back toward a defended set point within one to two heartbeats.
Trigger a pressure disturbance such as standing up or a hemorrhage event, adjust the baroreflex gain (sensitivity) slider to see stronger or weaker correction, and watch the firing-rate, heart-rate, and blood-pressure traces settle back toward the 120/80 mmHg target.
Carotid sinus baroreceptor signals were first shown to control blood pressure in the 1920s by Heinrich Ewald Hering and Corneille Heymans, work that earned Heymans the 1938 Nobel Prize in Physiology or Medicine, decades before the reflex arc's millisecond-scale timing could be directly measured.