The simulation shows a dynamic model of blood buffering in which you can raise or lower carbon dioxide and bicarbonate levels and watch pH shift in real time according to the Henderson-Hasselbalch relationship, alongside visual cues for the four major acid-base disorders.
Use the sliders to adjust PaCO2 and plasma bicarbonate independently, or select a preset scenario such as hyperventilation or diabetic ketoacidosis, and observe how the resulting pH, compensation response, and disorder classification update instantly.
Interactive sliders for PaCO2 and bicarbonate plus disorder presets let you explore how respiratory and metabolic changes drive blood pH.
A person at rest produces roughly 15,000 to 20,000 millimoles of carbon dioxide per day from cellular respiration alone, all of which must be buffered and exhaled continuously just to keep blood pH within its narrow 7.35 to 7.45 range.
The simulation shows a dynamic model of blood buffering in which you can raise or lower carbon dioxide and bicarbonate levels and watch pH shift in real time according to the Henderson-Hasselbalch relationship, alongside visual cues for the four major acid-base disorders.
The simulation shows a dynamic model of blood buffering in which you can raise or lower carbon dioxide and bicarbonate levels and watch pH shift in real time according to the Henderson-Hasselbalch relationship, alongside visual cues for the four major acid-base disorders.
Use the sliders to adjust PaCO2 and plasma bicarbonate independently, or select a preset scenario such as hyperventilation or diabetic ketoacidosis, and observe how the resulting pH, compensation response, and disorder classification update instantly.
A person at rest produces roughly 15,000 to 20,000 millimoles of carbon dioxide per day from cellular respiration alone, all of which must be buffered and exhaled continuously just to keep blood pH within its narrow 7.35 to 7.45 range.