IV Ketamine Infusion Protocol

Weight-based dosing and monitoring for treatment-resistant depression across a 6-infusion course.

Current Stage

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Calculated dose

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Infusion time left

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Infusions completed

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Response likelihood

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Patient weight (kg)70

Infusion number in course1

IV bag / ketamine solution

Infusion line & drip chamber

Patient monitoring readouts

Completed course infusion

Current / upcoming infusion

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Establishing Baseline Severity Before Ketamine Induction

A short placeholder line on baseline depression scoring before treatment.

MADRS: Primary scale (Short placeholder note.)
≤7 days: Screening window (Short placeholder note.)
Psychosis hx: Exclusion check (Short placeholder note.)
BP/HR: Baseline vitals (Short placeholder note.)

Screening and baseline severity scoring

Short placeholder paragraph describing baseline severity scoring steps.

Weight-Based Dosing at 0.5 mg/kg Racemic Ketamine

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0.5 mg/kg: Standard dose (Short placeholder note.)
100 mL NS: Diluent volume (Short placeholder note.)
40 min: Pump rate (Short placeholder note.)
~60 mg: Max single dose (Short placeholder note.)

Calculating and preparing the infusion dose

Short placeholder paragraph describing weight-based dose preparation.

40-Minute Continuous IV Infusion With Vital Monitoring

A short placeholder line on monitoring during the 40-minute infusion.

40 min: Infusion length (Short placeholder note.)
Every 5 min: Vitals interval (Short placeholder note.)
~30 min: Post-obs time (Short placeholder note.)
CADSS: Dissociation tool (Short placeholder note.)

Vital sign and dissociation monitoring protocol

Short placeholder paragraph describing monitoring during infusion.

Six Infusions Scheduled Across Two to Three Weeks

A short placeholder line on the six-infusion induction course.

6 infusions: Course length (Short placeholder note.)
2–3 weeks: Course duration (Short placeholder note.)
2–3x/week: Typical frequency (Short placeholder note.)
Tracked: Cumulative dose (Short placeholder note.)

Spacing and tracking the induction course

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Scoring Response and Planning Maintenance Infusions

A short placeholder line on response assessment and maintenance dosing.

≥50% drop: Response cutoff (Short placeholder note.)
MADRS ≤10: Remission cutoff (Short placeholder note.)
q2–4 wks: Maintenance freq (Short placeholder note.)
Ongoing: Relapse watch (Short placeholder note.)

Assessing response and scheduling maintenance care

Short placeholder paragraph describing response assessment and maintenance planning.

Short placeholder callout about durability of response and maintenance dosing.