Occupational Asthma — 3D

IgE-mediated respiratory sensitization inside a 3D bronchial airway — from first exposure to remodeling

Current Stage
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Serum IgE Titer
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Airway Resistance
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FEV1 % Predicted
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Sensitization Risk
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Sensitizer ConcentrationHigh
Exposure Duration24 months
Sensitizer particle / hapten
Dendritic / antigen-presenting cell
Th2 lymphocyte
Plasma cell / IgE antibody
Mast cell (armed / degranulating)
Bronchial wall / remodeling
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