Fecal-Oral Spread of Coxsackievirus
Placeholder: contaminated hands and surfaces carry virus to the mouth.
- Daycare: Primary setting (Placeholder short note)
- Weeks: Shedding duration (Placeholder short note)
- High: Hand hygiene effect (Placeholder short note)
- Summer/Fall: Peak season (Placeholder short note)
Route mechanics
Placeholder: stool-to-hand-to-mouth cycle drives community spread.
Placeholder: handwashing sharply cuts transmission chains.
Respiratory Droplet Spread
Placeholder: coughs and sneezes disperse infectious droplets nearby.
- ~1-2 m: Droplet range (Placeholder short note)
- Hours: Airborne survival (Placeholder short note)
- Early days: Contagious window (Placeholder short note)
- Moderate: Mask benefit (Placeholder short note)
Route mechanics
Placeholder: oral/nasal secretions carry virus during acute illness.
Placeholder: crowded indoor settings raise droplet exposure risk.
Viral Replication in the Gut
Placeholder: virus multiplies in lymphoid tissue of the intestine.
- 3-6 days: Incubation period (Placeholder short note)
- Peyer patches: Replication site (Placeholder short note)
- Day 2-3: Viremia onset (Placeholder short note)
- Week 1-2: Shedding peak (Placeholder short note)
Replication dynamics
Placeholder: enterovirus amplifies before spreading systemically.
Placeholder: viremia precedes visible skin and mouth lesions.
Vesicular Rash on Hands and Feet
Placeholder: small tender blisters appear on palms and soles.
- 3-7 mm: Typical lesion size (Placeholder short note)
- Palms/soles: Distribution (Placeholder short note)
- ~7-10 days: Duration (Placeholder short note)
- Mild-moderate: Pain level (Placeholder short note)
Rash pattern
Placeholder: lesions cluster on acral skin, sparing the trunk.
Placeholder: palm/sole distribution is a classic diagnostic clue.
Oral Vesicles and Ulcers
Placeholder: painful ulcers develop on tongue and inside cheeks.
- Tongue/gums: Common sites (Placeholder short note)
- Often first: Onset vs skin rash (Placeholder short note)
- Reduced intake: Feeding impact (Placeholder short note)
- ~1 week: Healing time (Placeholder short note)
Oral distribution
Placeholder: shallow ulcers cause pain and drooling in children.
Placeholder: oral pain often precedes hand-foot skin findings.