Pre-Challenge Risk Assessment
Baseline screening decides who is safe to challenge today.
- Required: History review (Placeholder short note)
- Checked: Baseline spirometry (Placeholder short note)
- Reviewed: IgE / SPT level (Placeholder short note)
- Yes: Consent obtained (Placeholder short note)
Screening before dosing starts
Placeholder short paragraph on pre-challenge eligibility checks.
Staged Dose Administration Under Monitoring
Doses escalate stepwise with rest intervals between each one.
- 6: Dose steps (Placeholder short note)
- ~20 min: Interval per step (Placeholder short note)
- 3 mg: Starting dose (Placeholder short note)
- 1000 mg: Top dose (Placeholder short note)
Escalation schedule under supervision
Placeholder short paragraph describing stepwise dose increases.
Real-Time Observation for Reaction Signs
Staff watch skin, breathing, and gut symptoms after each dose.
- Every step: Vitals checked (Placeholder short note)
- Continuous: Skin checks (Placeholder short note)
- Continuous: Airway checks (Placeholder short note)
- 2 hrs post: Observation window (Placeholder short note)
What monitoring looks for
Placeholder short paragraph on symptom categories tracked.
Reaction Management If It Occurs
Dosing halts and treatment starts the moment symptoms appear.
- Immediate: Stop dosing (Placeholder short note)
- On hand: Antihistamine (Placeholder short note)
- On hand: Epinephrine (Placeholder short note)
- Yes: Physician present (Placeholder short note)
Emergency response protocol
Placeholder short paragraph on graded reaction treatment steps.
Outcome Determination — Pass/Fail Challenge
Full dose tolerated confirms tolerance; reaction confirms allergy.
- No reaction: Pass criteria (Placeholder short note)
- Objective signs: Fail criteria (Placeholder short note)
- 2 hrs: Post-challenge watch (Placeholder short note)
- Yes: Result documented (Placeholder short note)
Deciding the final result
Placeholder short paragraph on how outcome is documented.