Villous Atrophy Healing

Marsh 0–IIIc: villi regrowth on a gluten-free diet, simulated over time.

Current Stage

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Current Marsh stage

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Villous height recovery

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Crypt hyperplasia

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Est. full recovery

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Months gluten-free0

Initial Marsh severityMarsh 0

Flattened / damaged epithelium

Regrowing villous tip

Healthy finger-like villus

Intraepithelial lymphocytes

Hyperplastic crypt

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Marsh IIIc — Total Villous Atrophy

Placeholder: gluten-driven flattening destroys the absorptive villous surface.

~0%: Villous height (Placeholder short note)
Max: Crypt depth (Placeholder short note)
High: IELs (Placeholder short note)
Severe: Symptom load (Placeholder short note)

Baseline severe damage

Placeholder: flattened mucosa with dense lymphocytic infiltrate at baseline.

Placeholder: diagnosis stage before diet change begins.

Partial Atrophy — Early Structural Rebuild

Placeholder: blunted villi start regaining modest height.

~30%: Villous height (Placeholder short note)
High: Crypt depth (Placeholder short note)
1–3 mo: Timeframe (Placeholder short note)
Moderate: Symptom load (Placeholder short note)

Early structural rebuild

Placeholder: shortened villous stubs emerge after gluten exclusion.

Placeholder: earliest histologic sign of healing response.

Early Recovery — Villous Elongation

Placeholder: villous stubs lengthen while lymphocytes remain elevated.

~55%: Villous height (Placeholder short note)
Elevated: Crypt depth (Placeholder short note)
3–9 mo: Timeframe (Placeholder short note)
Mild: Symptom load (Placeholder short note)

Villous elongation phase

Placeholder: progressive lengthening restores partial absorptive surface.

Placeholder: lymphocyte counts lag behind structural repair.

Crypt Hyperplasia Resolving

Placeholder: crypt depth ratio normalizes as turnover slows.

~80%: Villous height (Placeholder short note)
Falling: Crypt depth (Placeholder short note)
9–18 mo: Timeframe (Placeholder short note)
Minimal: Symptom load (Placeholder short note)

Crypt-villus ratio recovery

Placeholder: crypt hyperplasia declines toward the normal ratio.

Placeholder: ratio normalization tracks mucosal healing closely.

Complete Villi Recovery

Placeholder: tall finger-like villi and normal crypts restored.

100%: Villous height (Placeholder short note)
Normal: Crypt depth (Placeholder short note)
12–24 mo: Timeframe (Placeholder short note)
Resolved: Symptom load (Placeholder short note)

Full mucosal normalization

Placeholder: histology matches a gluten-naive healthy mucosa.

Placeholder: full recovery timing varies by patient age.