Identifying the Current Illness Phase
Placeholder: phase drives every downstream drug choice.
- 3: Phases tracked (mania, depression, maintenance)
- Mood state: Key input (placeholder metric)
- Ongoing: Reassessment (placeholder cadence)
- Clinical exam: Tool (placeholder source)
Why phase matters first
Placeholder text: phase sets the treatment target before any drug is picked.
Lithium Suitability Across Phase and Comorbidity
Placeholder: lithium is strong in mania and maintenance, weaker in depression.
- Mania: Best phase (placeholder strength)
- High: Renal risk (placeholder caution)
- Levels: Monitoring (placeholder need)
- Notable: Anti-suicide effect (placeholder benefit)
Lithium strengths and cautions
Placeholder text: renal and thyroid comorbidity lower the lithium score sharply.
Valproate Suitability Across Phase and Comorbidity
Placeholder: valproate excels acutely in mania, less so in depression.
- Mania: Best phase (placeholder strength)
- Moderate: Hepatic risk (placeholder caution)
- Avoid: Pregnancy (placeholder restriction)
- Fast: Onset (placeholder speed)
Valproate strengths and cautions
Placeholder text: hepatic comorbidity moderately lowers the valproate score.
Lamotrigine Suitability Across Phase and Comorbidity
Placeholder: lamotrigine favors depression and maintenance, weak in mania.
- Depression: Best phase (placeholder strength)
- Slow: Titration (placeholder pace)
- Low-mod: Rash risk (placeholder caution)
- Minimal: Comorbidity impact (placeholder tolerance)
Lamotrigine strengths and cautions
Placeholder text: comorbidity burden barely changes the lamotrigine score.
Combining Phase and Comorbidities into a Recommendation
Placeholder: the highest suitability score wins the final pick.
- 2: Inputs used (phase and comorbidity)
- 3 scores: Outputs (one per agent)
- Max score: Decision rule (placeholder logic)
- Periodic: Review (placeholder cadence)
Reading the final recommendation
Placeholder text: reassess as phase shifts or comorbidities change.
Placeholder highlight: no single agent wins every scenario.