This model shows a cross-section of skin — dermis, epidermis and the outer stratum corneum — with a simulated layer of honey applied as a face mask. Honey is a strong humectant: its sugars pull and hold water at the skin surface, while its low pH, hydrogen-peroxide production and trace compounds like methylglyoxal (concentrated in Manuka honey) give it mild antimicrobial activity against surface bacteria.
Medical-grade Manuka honey is used in licensed wound dressings — its combination of high sugar osmolarity, acidity and hydrogen-peroxide production creates an environment that is inhospitable to many common bacteria, which is part of why honey has been used topically for thousands of years.
A cross-section of skin — dermis, epidermis and stratum corneum — with a simulated honey mask on top, showing how exposure time, mask thickness and honey type change moisture retention, surface pH and microbial activity.
Honey's humectant sugars draw and hold water at the skin surface over time, while its natural acidity and hydrogen-peroxide production create mild antimicrobial activity — strongest in Manuka honey, weaker in heavily processed honey.
Pick a honey type, drag exposure time forward to watch moisture droplets accumulate and surface microbes shrink, and adjust mask thickness to see how an occlusive layer changes the outcome.
Medical-grade Manuka honey is used in licensed wound dressings, thanks to its combination of high osmolarity, low pH and hydrogen-peroxide generation that many common bacteria struggle to tolerate.