CAR-T Engineering

Chimeric Antigen Receptor T-cells are gene-edited ex vivo with lentiviral vectors and reinfused. Each CAR-T hunts and lyses matched cancer cells.

CAR-T Cells

Cancers Killed

Tumor Burden

—%

CAR Expression

—%

Tumor Eradication Progress 0%

CAR Affinity (scFv KD)High

T-Cell DoseMedium

Cytokine Boost (IL-2)0%

Lentiviral Edit

scFv CAR

Immunotherapy

Cell Types

CAR-T Cell (armed)

Naive T-cell

Cancer Cell

Dying Cancer Cell

Cytokine Burst