Assessing Candidacy Before Isotretinoin Therapy Begins
Short placeholder: severe acne patient screened for pregnancy potential first.
- High: Teratogenic risk (placeholder caption text here)
- 1st: Screening step (placeholder caption text here)
- CBP: Population affected (placeholder caption text here)
- iPLEDGE: Program name (placeholder caption text here)
Why candidacy screening matters
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iPLEDGE Enrollment and Dual Contraception Counseling
Short placeholder: patient education plus two contraception methods required.
- 2: Contraception methods (placeholder caption text here)
- Multiple: Education topics (placeholder caption text here)
- REMS: Registry (placeholder caption text here)
- Required: Consent forms (placeholder caption text here)
Enrollment requirements overview
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The Monthly Pregnancy Test Verification Cycle
Short placeholder: negative test required in-window before each refill.
- 7 days: Test window (placeholder caption text here)
- Lab/office: Verification (placeholder caption text here)
- Monthly: Cycle frequency (placeholder caption text here)
- Test-linked: Refill gate (placeholder caption text here)
How the verification loop works
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Ongoing Monitoring Across the Full Treatment Course
Short placeholder: 30-day supply caps enforce monthly prescriber check-ins.
- 5-6 mo: Course length (placeholder caption text here)
- 30 days: Max supply (placeholder caption text here)
- Monthly: Prescriber visits (placeholder caption text here)
- Ongoing: Adherence checks (placeholder caption text here)
Monitoring cadence details
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Program Outcomes — Exposed Pregnancy Rate Reduction
Short placeholder: monthly checks cut exposed pregnancies, not eliminated.
- Higher: Pre-program rate (placeholder caption text here)
- Lower: iPLEDGE-era rate (placeholder caption text here)
- Nonzero: Residual risk (placeholder caption text here)
- Ongoing: Program status (placeholder caption text here)
What the outcome data shows
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